Gene description for SPPL2A
Gene name signal peptide peptidase like 2A
Gene symbol SPPL2A
Other names/aliases IMD86
IMP3
PSL2
Species Homo sapiens
 Experiment description of studies that identified SPPL2A in Retinal pigment epithelial cells

1
Experiment ID2699
Identified moleculeProtein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35333565   
OrganismHomo sapiens
Experiment descriptionLAMP2A regulates the loading of proteins into exosomes
AuthorsFerreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year2022
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID2700
Identified moleculeProtein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35333565   
OrganismHomo sapiens
Experiment descriptionLAMP2A regulates the loading of proteins into exosomes
AuthorsFerreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year2022
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

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